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Olive oil can help reverse the damage associated with a high-fat diet
Benefits which carries virgin olive oil are known not from today. As it turns out, in addition to the more familiar advantages of this great vegetable fat, it has less known biological and physiological mechanisms that act on our body extremely positively. According to recent studies, a compound which contains a virgin olive oil can reverse the adverse effects posed by a diet high in fat.
According to a survey carried out on mice, virgin olive oil may reverse symptoms of the nonalcoholic liver disease.
Previous research has shown that olive oil, and especially virgin olive oil, can reduce the risk of cardiovascular diseases. Unfortunately, researchers have not found too many details on the mechanisms responsible for this significant relationship between olive oil and health benefits the cardiovascular system.
To explore this mystery, a team led by Dr. Rodrigo Valenzuela of the University of Chile in South America decided to investigate how the compound contained in virgin olive oil affects the health of mice.
The compound in question is hydroxytyrosol polyphenol with rich antioxidant properties, which combines the numerous health benefits associated with the consumption of olive oil.
Hydroxytyrosol – a compound contained in olive oil can have a protective effect on the liver.
The research team studied the effects of hydroxytyrosol on mice that were fed a diet rich in fats. In particular, certain enzymes have been considered that play a significant role in the synthesis of some polyunsaturated fatty acids.
Polyunsaturated fatty acids are beneficial to health since they help reduce the “bad” cholesterol, improve the health of the cardiovascular system, brain function and affect cell growth.
The so-called “bad” cholesterol, is known as low-density lipoprotein cholesterol – LDL. It is called “bad” cholesterol because it is a type of fat that often accumulates inside the arteries, and curing and blistering for a long time can cause numerous cardiovascular diseases.
High-density lipoprotein cholesterol – called “good,” in turn, transports cholesterol from other parts of the body to the liver, where it is processed and eliminated.
During the test, researchers from the University of Chile in South America were feeding four groups mice (each having 12 to 14 subjects rodents) using a high-fat diet (60% fat) or a control diet (10% fat). Also, some mice were treated with 5 mg hydroxytyrosol per kilogram body weight. The tests lasted 12 weeks.
Obtained by a team of researchers blood and tissues of the mice at the end of the experiment showed an interesting relationship. In studies, the scientist has analyzed the effect of diet on fatty acid composition, enzyme activity, and oxidative stress.
Hydroxytyrosol reverses the symptoms of the fatty liver disease.
In mice that were fed a high-fat diet, total cholesterol, and LDL increased, while HDL was maintained at a similar level. However, the addition of hydroxytyrosol in the diet seemed to reduce the negative impact of these types of cholesterol on the mice that took it.
A high-fat diet also appeared to increase insulin resistance markers, but those of the mice who were administered with the compound of olive oil, these markers were reduced. But they were not as low as in the mice consuming it regularly.
Importantly, mice with high-fat diets showed reduced levels of liver enzymes that helped synthesize polyunsaturated fatty acids. Decreased liver enzyme activity was associated with an imbalance of fatty acids in the liver, brain, and heart.
Mice whose diet has been enriched with hydroxytyrosol have shown enzymatic activity and a fatty acid composition similar to that obtained through the use of a regular diet. This may mean that the diet rich in olive oil can reverse the harmful effects of a high-fat diet.
The results seem to indicate that hydroxytyrosol could be a key element of the health benefits of olive oil extra virgin.
Mice fed a diet high in the fat, exhibit the symptoms of the non-alcoholic liver disease, which is combined with a noticeable reduction in the enzyme activity in the liver and the adverse effects of the fatty acid and organs. Similarly, oxidative stress associated with liver disease is also increased. But, as scientists say, promising research results, the use of regular doses of hydroxytyrosol in the diet can divert all these adverse effects, reduce the symptoms of liver disease and limit the negative effects seen in other organs.