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Hepatitis (non-viral origin, or severe) is a health problem caused by toxins, drugs or other chemical substances which damage cells, including liver cells – hepatocytes.
Non-viral hepatitis is a liver disease that occurs due to the appearance of inflammation, irritation or swelling of the liver cells. This disease is an increasing problem, due to the growing number of dietary supplements whose side effect can be an inflammation of the liver.
Acute hepatitis can destroy hepatocytes, which are up to 85% of the liver. These cells are responsible for the metabolism, detoxification and inactivation of harmful substances contained in medicines and the like. Hepatocytes remove substances from the blood, turning them so that they can be excreted by the kidneys in urine, or through the stool, with the bile.
The symptoms hepatitis
The symptoms, which displays hepatitis, typically occur suddenly, within a few days or weeks, by taking a harmful substance. In the early stages of hepatitis, symptoms can often be confused with the flu. The first symptoms are usually:
- abdominal pain, especially the upper right side of the – are frequently not very intense,
- nausea (as well as vomiting)
- general tiredness,
- loss of appetite,
- high temperature,
- muscle and joint pain,
- a significant and sudden weight loss.
Additional non-viral hepatitis symptoms may also be:
- yellowing of the skin and eyeballs – jaundice,
- dark urine,
- light and shade pale feces,
- clear liver enlargement or swelling,
- severe abdominal pain, appearing suddenly,
- frequent changes in mental condition – may appear confusion, drowsiness, dizziness,
- dysfunction of the brain – brain edema,
- in extreme cases, even death.
Complications of hepatitis may be different. Often the disease mildly passes after discontinuation of harmful substances. Minor damage to the liver is possible to regenerate – the liver is the fastest recovering organ in our body, but the appearance of scarring (fibrosis or cirrhosis) leads to tissue death, and they occur if inflammation of the liver is not treated.
Fibrosis as a complication of hepatitis is a serious liver damage, which is manifested in the formation of scars. A small number of them is not life threatening, but already a greater scarring can severely impair liver function.
In the case of cirrhosis of the liver, we are dealing with extensive scarring that impairs liver function. Another complication may also be a tumor of the liver, which appears as the chronic inflammation of the liver, increasing the risk of tumor mutations in the DNAs.
Among the complications associated with hepatitis should be distinguished as well liver failure, which may be one of the rare cases, however, can severely hamper the functioning of the liver.
Diagnosis and treatment of hepatitis
The first step in the treatment of non-viral hepatitis is to eliminate the source of inflammation. People who consumed or consume irritant liver substances should stop this.
To confirm the diagnosis, are needed, blood tests to assess levels of liver enzymes, which are an important sign of liver damage. Often, they are prescribed by a doctor corticosteroids, which allow reducing the inflammation. Unfortunately, in severe cases, it is necessary to perform a liver transplant.